Investigating the Toxicity and Histopatho-Morphological Alterations Induced by Cana Indica Extract on Clarias gariepinus Fingerlings

This study aimed to assess the toxic potentials and histopatho-morphological changes in Clarias gariepinus fingerlings exposed to the ethanolic extract of Cana indica. Upon introduction of the extract to the test media, significant variations were observed in the water quality parameters, following a concentration-dependent pattern. Behavioural changes and modifications in the gill tissues were evident in the exposed groups, with severe alterations observed, excluding the control group. Mortalities were recorded in a concentration-dependent manner, with the LC50 value estimated at 20.5 mg/l representing a log transformed concentration of 1.31mg/l. These findings underscore the potential toxicological impact of Cana indica extract on aquatic organisms, highlighting the need for further investigation into its environmental implications and management strategies.

Keywords: Cana indica, Clarias gariepinus, Toxicity, Histopatho-morphology, Fingerlings.