The Role of Genetics Mutations in Genes APP, CST3, ITM2B in Inducate Hereditary Cerebral Amyloid Angiopathy Syndrome

HCAA syndrome is a genetic disorder that can lead to gradual loss of intellectual function (mental decline), stroke, and other neurological problems in the middle of adulthood. The mutation in the APP gene, located in the long arm of chromosome 21 as 21q21.3, is the most common genetic cause of HCAA syndrome.

Keywords: HCAA syndrome, APP, CST3, ITM2B genes, Brain Disorder.