The Sea Star Igkappa Gene: Effects Against Mouse Tumoral Cells

The sea star Axial organ cells exert a spontaneous cytotoxicity against mouse cancerous cells (Leclerc and Luquet then Luquet and Leclerc (1983))
Recently, we discovered a sea star Igkappa gene with immune properties. This gene was inserted in a CMV(cytomegalovirus) and finally in a plasmid called « young » plasmid.

The induced« young » protein exerted a spontaneous cytotoxicity against Hela cells (cervix carcinoma cells), and at a significant degree against Mouse tumoral cells.