Burden of Helicobacter Pylori (H. Pylori) Disease in a Community in Sokoto State

Pyloric ulcer a public health disease important and is highly implicated with H. pylori hence the research to determine the prevalence of helicobacter pylori (H. pylori), induced peptic ulcer in sokoto metropolis. The sample for the study consisted of 150 (one hundred and fifty) adults’ females/males randomly drawn. Data collected were analyzed using descriptive statistic of frequency count, normative percentage and grand mean; as well as inferential statistics of chi-square (χ2). The level of significant was fixed at 0.05. Appropriate degrees of freedom were worked out. The antibody rapid test device (whole blood/serum/plasma) is a qualitative device based on immunoassay for the detection of H. pylori antibodies in the whole Blood, serum or plasma. In this test specimen followed by buffer is added to the specimen well of the test device. The specimen migrates chromatographically along the length of the test strip contained within the device and interacts with the reagents on the test strip.This research showed that prevalence of H.pylori infection is 38(25.3%). Among the 82 male’s clients 20(24%) tested positive, while among 68 females 18(26%) tested positive to H. pylori.There was a significance difference of the calculated chi-square (χ2=32.33 is greater than the tabulated χ2=3.841 at df=1, p<0.05). The prevalence of H. pylori induced ulcer among 93 symptomatic clients 21(22.8%) tested positive, while among 57 asymptomatic clients 17(29.8%) tested positive. There was a significance difference of the calculated chi-square (χ2=33.57 is greater than the tabulated χ2=3.841 at df=1, p<0.05). This may explain why the rate of infection is so high in poorer countries and in socio-economic groups since It is potentially spread by fecal contamination, characterized by crowded living conditions, poor sanitary conditions, and lack of clean water (Bujanover, 1996). Poor Personal hygiene is also very important since food preparers who may not perform adequate hand washing may be potential sources of infection (Hunt, 2011).

Keywords: Helicobacter pylori (H. pylori), symptomatic, asymptomatic.