Therapeutic Effects of Oral Sildenafil Citrate Verus Nitric Oxide Patch on Pregnant Women with a History of Recurrent Miscarriage

The present cohort study was planned to investigate the clinical effect of sildenafil citrate (SC) tablets as well as nitric oxide (NO) patch for treatment of first trimester pregnant women with a history of unexplained recurrent spontaneous abortion.

The survey was carried on 60 first trimester pregnant women with a history of recurrent miscarriage. The patientwas divided into two equal groups. The first patient group received SC 20 mg orally, 3 times/day and the second patient group received NO patch. We judged the effectiveness of this treatment on the patients. We establish that both oral SC and NO patch decreased the incidence of spontaneous recurrent first trimester abortion.

In ending, we report evidence that both oral SC and NO patch can offer and optional therapy for cases of spontaneous recurrent first trimester abortion.

Keywords: Sildenafil citrate; Nitric oxide patch; Unexplained recurrent spontaneous miscarriage; Abortion.