Dress Syndrome Induced by Antifimics Drugs: Literature Review and Case Report

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is an uncommon but potentially life-threatening adverse response to specific medications. Typical clinical features include fever, exanthema, lymphadenopathy, and eosinophilia, with possible involvement of vital organs. Adverse reactions may also result from antituberculosis drugs, presenting a risk to patients due to the potential necessity of temporarily discontinuing therapy. Such interruptions can compromise the efficacy of treatment and subsequently hinder patient recovery. We report a rare case of DRESS syndrome in a 16-year-old, triggered by first-line antituberculosis drugs, a rare case in pediatric population. Therapy was continued, and the patient’s condition resolved following the suspension of causal drugs and implementation of a modified therapeutic scheme.

Keywords: Antituberculosis Drugs, Drug Reaction with Eosinophilia and Systemic Symptoms (Dress), Tuberculosis.