Hungry Bone Syndrome after Surgical Treatment of Hyperparathyroidism in Dialysis Patients: About Two (2) Cases in Senegal

Introduction: Hungry bone syndrome (HBS) is a complication of hyperparathyroidism surgical management characterized by deep hypocalcaemia and hypophosphatemia secondary to a massive influx of calcium to an avid bone.

Observations: We report the cases of two (2) patients dialysed for chronic kidney disease (CKD) whose initial nephropathy is a hypertensive nephropathy. They posed the problem of CKD-mineral bone disorder (CKD-MBD) fibrous osteitis type with intact parathyroid hormone (PTH) up to 40N for which a subtotal parathyroidectomy (PTX) was performed with postoperative biological anomalies in favour of the diagnosis of hungry bone syndrome.

Conclusion: HBS still intervenes on osteopathies of intense turnover. Its treatment is difficult, based on prolonged calcium and vitamin D supplementation. However, perioperative therapeutic protocols settlement seems essential in order to minimize the risks of its occurrence.

Keywords: Hungry bone syndrome – secondary hyperparathyroidism – parathyroidectomy – dialysis.