Seroprevalence of Hepatitis B in Hemodialysis Patients and Associated Factors in N’Djamena

Introduction: Hepatitis B virus infection is a real public health problem worldwide, with around two billion people infected and 257 million chronic carriers. The lack of data on chronic hemodialysis patients in N’Djamena prompted this study, the aim of which was to improve the management of viral hepatitis B in chronic hemodialysis patients at the Centre Hospitalier Universitaire -Référence Nationale and the Centre Hospitalier Universitaire -Renaissance in N’Djamena.

Material and Methods: This was a descriptive cross-sectional study spread over a period of 8 years and 8months from March 2014 to November 2022. The variables described were sociodemographic, clinical and paraclinical.

Results: The prevalence of hepatitis B virus infection among chronic hemodialysis patients was 12.7%, with a male predominance and an M/F sex ratio of 1.6. The average age was 49. Seven patients were between 40 and 60 years old. Most patients were from urban areas. There were 10 married patients in this study. Eight patients were HBsAg-positive before starting dialysis. Four patients had been on dialysis for less than 2 years. However, 6 patients had been on dialysis for two to four years (2-4years). Transaminase levels were normal in 9 patients. Twelve patients had received at least one blood transfusion.

Conclusion: Hepatitis B virus infection is common in chronic hemodialysis patients, who are fragile and often polytransfused.

Keywords: HBV, Hemodialysis, Infection, atients, Chad.