Female Neonate Breasts Tc-99m Pertechnetate Uptake

This is an unusually encountered imaging finding on tc-99m pertechnetate thyroid scintigraphy for a female neonate. The study goal is further assessment of thyroid function test derangement that was identified in the routine well baby clinic screening. Neonatal breasts focal symmetrical tc-99m pertechnetate uptake was incidentally depicted. Tc-99m pertechnetate cellular uptake depends on the transmembrane sodium-iodide symporter mechanism and this is normally present in breast tissues. Maternal lactogenic hormones transplacental transportation leads to enhancement of the transmembrane sodium-iodide symporter mechanism (1, 2, 3). This transplacental hormonal transportation with resultant transmembrane sodium-iodide symporter mechanism enhancement are the reasons behind we have surprisingly seen in this thyroid scan.