Neonatal Lupus Erythematosus: Two Case Reports in a Single Centre

Author Details

Dr. Wee Ai Leen, Dr. Leong Kin Fon, Dr. Sabeera Begum

Journal Details

Published

Published: 10 December 2018 | Article Type :

Abstract

Neonatal lupus erythematous (NLE) is a rare autoimmune mediated disease that is associated with transplacental autoantibodies. It is characterised by cutaneous manifestations and may involve cardiac, haematologic, neurologic and hepatic abnormalities. We describe two cases with clinical, pathological and immunological findings compatible with neonatal lupus erythematosus, treatment and progress. Both their mothers were asymptomatic but were found to have autoantibodies. In view of the possible serious complications such as complete heart block, a high index of suspicion coupled with a thorough evaluation of both child and mother is required.

Keywords: Neonatal lupus erythematosus; antinuclear antibody (ANA); auto antibodies; anti-Ro; anti-La.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright © Author(s) retain the copyright of this article.

Statistics

135 Views

198 Downloads

Volume & Issue

Article Type

How to Cite

Citation:

Dr. Wee Ai Leen, Dr. Leong Kin Fon, Dr. Sabeera Begum. (2018-12-10). "Neonatal Lupus Erythematosus: Two Case Reports in a Single Centre." *Volume 1*, 2, 15-19