Utilization of Recombinant Human Bone Morphogenetic Protein on the Reconstruction of Critical Defect on Maxilla

Objective: The aim of this study was to report a case of utilization of recombinant human bone morphogenetic protein-2 on bony regeneration of anterior maxilla.

Case Report: 39 years old female patient, non-smoker and without systemic complication was referred to dental evaluation because of dental esthetic dissatisfaction. After clinical and tomographic examination a defect class III of Seibert was observed six months after extraction of teeth 12 and 11. Because of defect’s morphology augmentation by autogenous bone block was not allowed. Alveolar ridge augmentation was realized utilizing rhBMP-2. After 12 months a new tomography revealed bone augmentation that allowed implant installation.

Discussion: rhBMP-2 has been utilized for induction of bone formation for different critical defects including alveolar ridge defects.

Conclusion: The clinical results observed on this study allowed reconstruction of alveolar ridge and adequate tridimensional implant installation on anterior maxilla.

Keywords: maxilla; alveolar ridge augmentation; guided bone regeneration; recombinant human bone morphogenetic protein-2h.