Predictors of the Mortality of Patients Under Anesthesia for Postoperative Peritonitis in Kinshasa

Author Details

Raissa Assani, Wilfrid Mbombo, Christian Nantulu, Gibency Mfulani, Philomene Diyoyo, Didier Kandongo, Fiston Nganga, Marcel Kamwanga, Von Joslin Miteo, Judith Mbimbi, Laurence Bamporiki, Jerry Muluma, Denis Mutombo, Berthe Barhayiga

Journal Details

Published

Published: 31 July 2023 | Article Type : Research Article

Abstract

Background: Anesthesia for postoperative peritonitis is associated with significant mortality due to the risk of multiorgan failure. This study was conducted to find predictors of this mortality.

Methods: This is a multicenter documentary analytical study conducted from 01/01/2017 to 12/31/2021 in patients anesthetized for postoperative peritonitis. Sociodemographic, clinical, and evolutionary data were collected and analyzed with SPSS 23.0 using, depending on the type of data; t Student, chi-square and Fischer’s exact tests, logistic regression and Kaplan Meir curves for p˂0.05.

Results: Two hundred and one patients were included in the study, the average age was 30 years (SD: 19); there were more or less as many men as women (sex ratio 0.97); 28.4% had comorbidities; 62.7% were transferred from peripheral structures, of which 57.7% were operated on urgently with appendicitis as the main indication (30.8%); surgery performed by a junior in 59.2%. The mean recovery time was 10.25 days; consciousness was altered perioperatively in 30.3%; 58.2% were classified as ASA III; 33.8% ASA IV; all the patients were operated under general anesthesia with tracheal intubation using the association propofol-ketamine, suxamethonium, halogenated and fentanyl. Antibiotic therapy was empirical using the combination of C 3 G-Metronidazole (44.3%) and Piperacillin/tazobactam-aminoside (30.3%), complications were present intraoperatively in 55.2% and postoperatively in 41.8%; 5.5% irreversible cardiorespiratory arrest on induction. The overall mortality was 37.7%. Age > 65 years, ASA class > 3, impaired consciousness and the occurrence of intraoperative complications have proven to be predictors of mortality.

Conclusion: Mortality in this series, although significant, is low compared to previous studies and its predictors depend more on the patient’s condition and are relatively independent of anesthesia.

Keywords: Predictors, Mortality, Anesthesia, Postoperative peritonitis.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright © Author(s) retain the copyright of this article.

Statistics

479 Views

884 Downloads

Volume & Issue

Article Type

Research Article

How to Cite

Citation:

Raissa Assani, Wilfrid Mbombo, Christian Nantulu, Gibency Mfulani, Philomene Diyoyo, Didier Kandongo, Fiston Nganga, Marcel Kamwanga, Von Joslin Miteo, Judith Mbimbi, Laurence Bamporiki, Jerry Muluma, Denis Mutombo, Berthe Barhayiga. (2023-07-31). "Predictors of the Mortality of Patients Under Anesthesia for Postoperative Peritonitis in Kinshasa." *Volume 5*, 1, 10-26